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KMID : 0364019960290080867
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Korean Journal of Thoracic and Cardiovascular Surgery
1996 Volume.29 No. 8 p.867 ~ p.874
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Corelation Between Left Ventricular Peak Systolic Pressure/End-Systolic Volume Ratico and Symptomatic Improvement with Valve Replacement in Patients with Aortic Regurgitation and Enlarged End-Systolic Volume
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Abstract
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This study was designed to assess the left ventricular peak systolic pressure/end-systolic volume (PSP/ESV) ratio in predicting symptomatic improvement with valve replacement in patients with aortic regurgitation and enlarged left ventricular
volume.
We studied 21 patients (15 men and 6 women aged 15 to 60 years) with moderate or severe aortic regurgitation, no other cardiovascular abnormalities and left ventricular end-systolic volume over 60 ml/m*. In this group we assessed the preoperative
variables which routinely were measured at cardiac catheterization to predict symptomatic improvement with valve replacement. Six months after operation, symptoms were alleviated in 13 patients(62%), and unchanged in 8(38%).
By multivariate analysis. The PSP/ESY ratio was a strong predictor for functional class 6 months after surgery(p=0.005) and also for change in functional class prior to an operation to 6 months postoperatively(p=0032). By 6 months after receiving
valve
replacement, all patients with a ratio over 1.71 mmHg/ml/m*, 40% were in functional class III.
The PSP/ESV ratio may help to predict which patients with aortic regurgitation and enlarged left ventricular end-systolic volume will have symptomatic improvement with valve replacement.
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